Format

Send to

Choose Destination
See comment in PubMed Commons below
Genome Announc. 2014 Nov 13;2(6). pii: e01161-14. doi: 10.1128/genomeA.01161-14.

Genome Sequence of the Anterograde-Spread-Defective Herpes Simplex Virus 1 Strain MacIntyre.

Author information

1
moriah@psu.edu.
2
Department of Molecular Biology, the Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.
3
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, USA.
4
Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA.

Abstract

We used paired-end Illumina deep sequencing and de novo assembly to determine the genome sequence of herpes simplex virus 1 (HSV-1) strain MacIntyre (aka McIntyre). The MacIntyre strain originated from the brain of a patient with lethal HSV encephalitis and has a unique limitation in its neuronal spread, moving solely in the retrograde direction.

PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for PubMed Central
    Loading ...
    Support Center