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Cornea. 2015 Jan;34(1):87-9. doi: 10.1097/ICO.0000000000000296.

Treatment of ocular surface squamous neoplasia with topical Aloe vera drops.

Author information

1
*Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, PA; and †Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, FL.

Abstract

PURPOSE:

To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.

METHODS:

A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.

RESULTS:

The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.

CONCLUSIONS:

Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

PMID:
25393094
DOI:
10.1097/ICO.0000000000000296
[Indexed for MEDLINE]

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