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Quant Imaging Med Surg. 2014 Oct;4(5):397-406. doi: 10.3978/j.issn.2223-4292.2014.09.04.

The role of magnetic resonance imaging in hypertrophic cardiomyopathy.

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1 Department of Radiology, 2 Department of Cardiology, Heart of England NHS Trust, Birmingham, UK.


Hypertrophic cardiomyopathy (HCM) is the most common inheritable cardiac disorder, with an estimated prevalence of 1:500 in the general population. Most cases of HCM are phenotypically expressed in adolescence or early adulthood but age-related penetrance with certain phenotypes is increasingly recognized. Clinical manifestations of HCM are usually the result of systolic and/or diastolic dysfunction, left ventricular outflow tract (LVOT) obstruction, arrhythmias and sudden cardiac death (SCD). In recent years magnetic resonance imaging (MRI) has become established as an important tool for the evaluation of suspected HCM as it can reliably establish the diagnosis, help distinguish HCM from other causes of left ventricular hypertrophy (LVH) and identify those patients at greatest risk of SCD. This article reviews the current status of MRI in the evaluation of the HCM patient including imaging protocols, disease characterization and the emerging role of MRI for risk stratification and proband screening.


Hypertrophic cardiomyopathy (HCM); magnetic resonance imaging (MRI); sudden cardiac death (SCD)

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