Purtscher-like retinopathy in association with metastatic pancreatic adenocarcinoma and capecitabine therapy

Retin Cases Brief Rep. 2013 Summer;7(3):196-7. doi: 10.1097/ICB.0b013e318280b034.

Abstract

Purpose: To report a case of Purtscher-like retinopathy in association with capecitabine chemotherapy for metastatic pancreatic adenocarcinoma.

Methods: Case report.

Results: Bilateral retinal hemorrhages and cotton-wool spots in a predominantly juxtapapillary distribution were observed coincident with decreased vision. There was gradual improvement of the retinopathy and patient's vision over several months until the time of death.

Conclusion: Metastatic pancreatic cancer and capecitabine, a fluoropyrimidine chemotherapeutic agent, are a rare cause of Purtscher-like retinopathy.