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Physiol Meas. 2014 Dec;35(12):2415-28. doi: 10.1088/0967-3334/35/12/2415. Epub 2014 Nov 12.

On estimating the directionality distribution in pedicle trabecular bone from micro-CT images.

Author information

1
Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto, M5S 3G9, Toronto, Canada. Spinesonics Medical Inc, 411-112 College St, M5G 1L6, Toronto, Ontario, Canada.

Abstract

Our interest in the trabecular alignment within bone stems from the need to better understand the manner in which it can affect ultrasound propagation, particularly in pedicles. Within long bones it is well established that trabecular structures are aligned in an organized manner associated with the direction of load distribution; however, for smaller bones there are limited alignment studies. To investigate the directionality distribution in a quantitative manner we used a micro-CT to obtain three-dimensional (3D) structural data and developed analytical methods based on the special properties of Gabor filters. Implementation of these techniques has been developed and tested on a variety of simulated images as well as on 3D structures whose geometry is well-defined. To test the use of this technique we compared the results obtained on vertebral body trabecular bone with visual directionality and previous measurements by others. The method has been applied to six human pedicle samples in two orthogonal planes with results that provide reasonable proof-of-principle evidence that the method is well suited for estimating the directionality distribution within pedicle bones.

PMID:
25391037
DOI:
10.1088/0967-3334/35/12/2415
[Indexed for MEDLINE]

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