Purpose: The purpose of this study is to report a case of spontaneous flattening of macular schisis in a patient affected by Goldmann Favre syndrome (GFS).
Methods: A case report.
Results: A young boy affected by GFS came for a follow-up visit 10 years after the diagnosis. Spontaneous flattening of macular schisis, posterior hyaloid detachment, and visual acuity improvement from 20/200 to 20/80 were observed in the left eye.
Conclusion: The observed spontaneous resolution of schisis in GFS, a rare inherited vitreoretinal dystrophy, suggests that an abnormality of the vitreoretinal interface could be the origin of macular schisis in this patient. This observation, reported for the first time to our knowledge, also leads to the hypothesis that the inconsistent presence of schisis in patients with GFS may not be a simple difference in phenotype but rather corresponds to different evolutional stages of the macula alterations in patients affected by GFS.