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J Int Soc Sports Nutr. 2014 Nov 7;11(1):44. doi: 10.1186/s12970-014-0044-9. eCollection 2014.

Effects of energy drink major bioactive compounds on the performance of young adults in fitness and cognitive tests: a randomized controlled trial.

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Indeportes Antioquia and School of Nutrition and Dietetics, University of Antioquia, UdeA, Calle 70 No 52-21, Medellín, Colombia.
Colcafé S.A.S, Medellín, Colombia.
Indeportes Antioquia, Medellín, Colombia.
Physiology and Biochemistry Research Group-Physis, Department of Physiology and Biochemistry, Faculty of Medicine, University of Antioquia, Medellín, Colombia.
Exercise Physiology Laboratory from Indeportes Antioquia and Physiology and Biochemistry Research Group-Physis, University of Antioquia, Medellín, Colombia.



The consumption of beverages containing caffeine and taurine before exercising has been associated with increased physical and psychological performances and has been promoted to support the emotional state and provide vitality to consumers. However, there are contradictory results on these issues, it is not clear the effect of every major compound in relation to the whole effect of the beverages and there is a lack in knowledge about their degree of safety for consumption.


This study used a double-blind, placebo controlled, randomized, crossover design. Fourteen male volunteer soldiers from the Colombian army performed different tests to measure their cardiorespiratory fitness (VO2max and maximum heart rate), time to exhaustion, strength (isometric strength), power (vertical jump), concentration (Grid test) and memory (Digits test) after drinking 250 ml of one of the following beverages: one with 80 mg caffeine, one with 1000 mg taurine, one with 80 mg caffeine plus 1000 mg taurine, a commercial energy drink (Red Bull®) or a placebo drink. Subjects were caffeine-consumers that avoided caffeine during the day of evaluation. All beverages were matched in flavor and other organoleptic properties to the commercial one, were bottled in dark plastic bottles and were administered in identical conditions to the participants. Differences between treatments were assessed using repeated measures and analysis of variance.


The mean ± SD values of VO2max, maximum heart rate, time to exhaustion, right handgrip strength, left handgrip strength, vertical jump, Grid test and Digits test were 61.3 ± 6.2 ml/kg.min, 196 ± 6.8 beats per min, 17 ± 1.2 min, 56.8 ± 6.6 kgf, 53.1 ± 5.9 kgf, 41.1 ± 3.8 cm, 19.9 ± 5.9 observed digits and 10.9 ± 3.1 remembered digits after drinking a placebo drink. Comparisons among the commercial drink, caffeine, taurine, caffeine plus taurine and placebo treatments did not show statistically differences in the results of the performed tests. No adverse effects were reported by the participants.


The consumption of caffeine (80 mg) and taurine (1000 mg) or their combination does not increase the physical and cognitive ability in young adults during exercise.


Caffeine; Cognitive ability; Energy drink; Physical condition; Taurine

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