Format

Send to

Choose Destination
Biochem Biophys Res Commun. 1989 Feb 28;159(1):312-6.

Alternative splicing of human insulin receptor messenger RNA.

Author information

1
Howard Hughes Medical Institute, Department of Biochemistry, University of Chicago, IL 60637.

Abstract

The polymerase chain reaction has been used to examine alternative splicing of human insulin receptor (hINSR) mRNA. Alternative splicing of a 36 base pair exon, exon 11, generates hINSR transcripts encoding receptor isoforms which differ in sequence at the C-terminal end of the insulin-binding alpha-subunit. This process appears to be tissue-specific and, in addition, may be developmentally regulated.

PMID:
2538124
DOI:
10.1016/0006-291x(89)92439-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center