Format

Send to

Choose Destination
Nature. 1989 Feb 23;337(6209):709-16.

The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution.

Author information

1
Laboratory of Molecular Biophysics, Oxford, UK.

Abstract

The structure of foot-and-mouth disease virus has been determined at close to atomic resolution by X-ray diffraction without experimental phase information. The virus shows similarities with other picornaviruses but also several unique features. The canyon or pit found in other picornaviruses is absent; this has important implications for cell attachment. The most immunogenic portion of the capsid, which acts as a potent peptide vaccine, forms a disordered protrusion on the virus surface.

PMID:
2537470
DOI:
10.1038/337709a0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center