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Mol Biol Cell. 2014 Nov 5;25(22):3466-9. doi: 10.1091/mbc.E14-03-0790.

Nuclear physics (of the cell, not the atom).

Author information

1
Program in Cell and Developmental Dynamics, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 thoru.pederson@umassmed.edu john-marko@northwestern.edu.
2
Department of Molecular Biosciences and Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208 thoru.pederson@umassmed.edu john-marko@northwestern.edu.

Abstract

The nucleus is physically distinct from the cytoplasm in ways that suggest new ideas and approaches for interrogating the operation of this organelle. Chemical bond formation and breakage underlie the lives of cells, but as this special issue of Molecular Biology of the Cell attests, the nonchemical aspects of cell nuclei present a new frontier to biologists and biophysicists.

PMID:
25368422
PMCID:
PMC4230604
DOI:
10.1091/mbc.E14-03-0790
[Indexed for MEDLINE]
Free PMC Article

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