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Sarcoidosis Vasc Diffuse Lung Dis. 2014 Oct 20;31(3):191-7.

Idiopathic Pulmonary Fibrosis (IPF) incidence and prevalence in Italy.

Author information

1
Departement of Epidemiology, Regional Health Service of Lazio, Rome. n.agabiti@deplazio.it.

Abstract

BACKGROUND:

Studies of Idiopathic Pulmonary Fibrosis (IPF) epidemiology show regional variations of incidence and prevalence; no epidemiological studies have been carried out in Italy.

OBJECTIVE:

To determine incidence and prevalence rates of IPF in the population of a large Italian region.

METHODS:

in this cross-sectional study study data were collected on all patients of 18 years of age and older admitted as primary or secondary idiopathic fibrosing alveolitis (ICD9-CM 516.3) to Lazio hospitals, from 1/1/2005 to 31/12/2009, using regional hospital discharge, population and cause of death databases. Reporting accuracy was assessed on a random sample of hospital charts carrying the ICD9-CM 516.3, 516.8, 516.9 and 515 codes, by reviewing radiology and pathology findings to define cases as IPF "confident", "possible" or "inconsistent".

RESULTS:

Annual prevalence and incidence of IPF were estimated at 25.6 per 100,000 and 7.5 per 100,000 using the ICD9-CM code 516.3 without chart audit while they were estimated at 31.6 per 100,000 and at 9,3 per 100,000 for the IPF "confident" definition after hospital chart audit.

CONCLUSION:

The data provide a first estimate of IPF incidence in Italy and indicate that incidence and prevalence in southern European regions may be similar to those observed in northern Europe and North America.

PMID:
25363218
[Indexed for MEDLINE]

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