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Front Plant Sci. 2014 Oct 14;5:522. doi: 10.3389/fpls.2014.00522. eCollection 2014.

Rho family GTPase-dependent immunity in plants and animals.

Author information

1
Laboratory of Plant Molecular Genetics, Nara Institute of Science and Technology Ikoma, Japan.
2
College of Pharmaceutical Sciences, Ritsumeikan University Kusatsu, Japan.

Abstract

In plants, sophisticated forms of immune systems have developed to cope with a variety of pathogens. Accumulating evidence indicates that Rac (also known as Rop), a member of the Rho family of small GTPases, is a key regulator of immunity in plants and animals. Like other small GTPases, Rac/Rop GTPases function as a molecular switch downstream of immune receptors by cycling between GDP-bound inactive and GTP-bound active forms in cells. Rac/Rop GTPases trigger various immune responses, thereby resulting in enhanced disease resistance to pathogens. In this review, we highlight recent studies that have contributed to our current understanding of the Rac/Rop family GTPases and the upstream and downstream proteins involved in plant immunity. We also compare the features of effector-triggered immunity between plants and animals, and discuss the in vivo monitoring of Rac/Rop activation.

KEYWORDS:

PAMPs-triggered immunity; Rac/Rop; effector-triggered immunity; plant immunity; small GTPase

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