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Int J Gynecol Cancer. 2014 Nov;24(9 Suppl 3):S109-16. doi: 10.1097/IGC.0000000000000294.

Trophoblastic disease review for diagnosis and management: a joint report from the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup.

Author information

1
*Department of Gynecology and Obstetrics, IRCCS San Raffaele Hospital, Milan, Italy; †Gynecologic Oncology Department, Catholic University of the Sacred Heart, Rome/Campobasso, Italy; ‡Gynecologic Oncology Group, The University of Texas MD Anderson Cancer Center, Houston, TX; §AGO Study Group, Gynecologic Oncology Center, Kiel, Germany; ∥Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands; ¶ANZGOG, Camperdown, New South Wales, Australia; #Department of Obstetrics and Gynecology, University of Hong Kong, Queen Mary Hospital, Hong Kong, People's Republic of China; **Centre de Référence des Maladie Trophoblastiques, Hospices Civils de Lyon, Lyon, France; ††Department of Obstetrics and Gynecology, Institute of Maternal and Child Health, Medical College, Calicut, India; ‡‡GTD unit, University Hospital of Caracas, Central University of Venezuela, Caracas, Venezuela; §§The Spanish Ovarian Cancer Research Group (GEICO), Fundación Instituto Valenciano de Oncología, Valencia, Spain; ∥∥Korean Gynaecologic Oncology Group, Seoul National University Hospital, Seoul, South Korea; ¶¶Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China; ##Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; and ***Charing Cross Trophoblastic Disease Centre, Departments of Histopathology and Medical Oncology, Charing Cross Campus of Imperial College London, London, United Kingdom.

Abstract

OBJECTIVE:

The objective of this study was to provide a consensus review on gestational trophoblastic disease diagnosis and management from the combined International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup.

METHODS:

A joint committee representing various groups reviewed the literature obtained from PubMed searches.

RESULTS AND CONCLUSIONS:

Guidelines were constructed on the basis of literature review. After initial diagnosis in local centers, centralization of pathology review and ongoing care is recommended to achieve the best outcomes.

PMID:
25341573
DOI:
10.1097/IGC.0000000000000294
[Indexed for MEDLINE]

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