Format

Send to

Choose Destination
World J Gastroenterol. 2014 Oct 21;20(39):14099-104. doi: 10.3748/wjg.v20.i39.14099.

Advances in treatment of ulcerative colitis with herbs: from bench to bedside.

Author information

1
Ping Wan, Hao Chen, Yuan Guo, Ai-Ping Bai, Department of Gastroenterology, the First Affiliated Hospital, Nanchang University, Nanchang 330006, Jiangxi Province, China.

Abstract

Ulcerative colitis (UC), an idiopathic inflammatory disorder in the colon, has become a clinical challenge, owing to the increasing incidence and poor prognosis. The conventional treatments for UC including aminosalicylates, corticosteroids, and immunosuppressants, induce remission in only half of patients. Meanwhile, the treatments often come with serious side effects which can be life-threatening. Herbal medicine, one of the most common traditional Chinese medicine modalities, has been introduced for centuries into clinical treatment of many human diseases such as infections and functional disorders. Recently, the potential effectiveness of herbs has been suggested as the treatment of UC, as shown by a variety of clinical trials and experimental studies. The herbs reported in the literature include aloe vera gel, butyrate, tormentil extracts, wheat grass juice, and curcumin. In the review, bioactivity of the herbs and their involvement in UC treatment are discussed.

KEYWORDS:

Herb medicine; Herbs; Inflammatory bowel disease; Safety; Therapy; Ulcerative colitis

PMID:
25339799
PMCID:
PMC4202341
DOI:
10.3748/wjg.v20.i39.14099
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Baishideng Publishing Group Inc. Icon for PubMed Central
Loading ...
Support Center