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Eur Arch Otorhinolaryngol. 2016 Feb;273(2):269-76. doi: 10.1007/s00405-014-3332-8. Epub 2014 Oct 22.

The role of brachytherapy in the treatment of squamous cell carcinoma of the head and neck.

Author information

1
Department of Otolaryngology-Head and Neck Surgery, PoznaƄ University of Medical Sciences, Poznan, Poland.
2
Department of Radiation Oncology, Division of Interventional Radiation Oncology, University Hospital Erlangen, Erlangen, Germany.
3
Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.
4
Department of Radiation Oncology, College of Medicine, University of Florida, Gainesville, FL, USA.
5
Department of Radiation Oncology, Beth Israel Medical Center and St. Luke's-Roosevelt Hospitals, New York, NY, USA.
6
University of Udine School of Medicine, Piazzale S. Maria della Misericordia, I-33100, Udine, Italy.
7
Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.
8
Department of Otolaryngology-Head and Neck Surgery, Philipp University, Marburg, Germany.
9
University of Udine School of Medicine, Piazzale S. Maria della Misericordia, I-33100, Udine, Italy. a.ferlito@uniud.it.

Abstract

Brachytherapy is a form of intensive local irradiation, allowing effective protection of surrounding structures with preservation of organ function and results in a favorable therapeutic ratio. It can be used alone, adjuvantly after surgery, and as a local boost in combination with external-beam radiation therapy. This paper is a literature review on the role of brachytherapy in the management of head and neck cancers with a special emphasis on papers published in the last 5 years. Technical details, effectiveness and potential toxicities of brachytherapy when used in different combinations with other therapeutic modalities and tumor sites are presented. Brachytherapy is an attractive treatment option in the management of primary malignancies and recurrent tumors in previously irradiated areas of the head and neck. It is effective and safe, and results in good functional and oncological outcomes.

KEYWORDS:

Brachytherapy; HDR; Head and neck cancers; PDR; Squamous cell carcinoma

PMID:
25338181
DOI:
10.1007/s00405-014-3332-8
[Indexed for MEDLINE]

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