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J Multidiscip Healthc. 2014 Oct 1;7:431-40. doi: 10.2147/JMDH.S67929. eCollection 2014.

Willingness to pay for a new drug delivery in Parkinson patients.

Author information

1
Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden ; Geriatric Department, Karolinska University Hospital, Stockholm, Sweden.
2
The Swedish Institute for Health Economics, Institute for Health Economics (IHE), Lund, Sweden.

Abstract

OBJECTIVE:

The Swedish reimbursement system operates a system where prices are set based on the expected value to the consumer. This value can be measured using willingness to pay (WTP).

AIM:

To assess Parkinson's disease (PD) patients' WTP for newly developed microtablets of levodopa in combination with a drug-delivering electronic device (M/E) compared to standard treatment with levodopa in combination with the COMT (catechol-O-methyl transferase)-inhibitor entacapone (L/e).

METHOD:

A total of 2,000 randomly included PD patients had a postal questionnaire covering demographics, disease-specific issues, views on medication and WTP in different hypothetical scenarios. The first scenario was M/E with no change in effects or side effects; the second scenario was M/E with same effect and less side effects; and the third scenario was M/E with improved effect and less side effects. These scenarios were coupled to different costs to choose from.

RESULTS:

A total of 999 patients (50%) responded, mean age of 71 years and a mean PD duration of 9 years. Of all respondents, 50% preferred M/E before L/e in scenario one with increasing preference to scenario three. The average monthly WTP among all respondents in scenario one was SEK 230 and SEK 226 in L/e, both with an almost longitudinal doubling up to scenario three. Duration of PD-related symptoms, high education, and high medication intake implied a higher WTP in all scenarios in contrast to age, sex, and extra doses of levodopa.

CONCLUSION:

WTP for M/E increased gradually with high medication intake and education as well as with expected increased reduction of PD symptoms.

KEYWORDS:

Parkinson’s disease; WTP; levodopa; microtablets

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