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Scand Cardiovasc J. 2014 Dec;48(6):339-42. doi: 10.3109/14017431.2014.976837.

Characteristics and outcome of patients with heart failure due to anabolic-androgenic steroids.

Author information

1
Department of Cardiothoracic Surgery, The Heart Centre , Rigshospitalet, Copenhagen , Denmark.

Abstract

OBJECTIVES:

The objective of the study was to analyse the outcome of patients with advanced heart failure due to abuse of anabolic-androgenic steroids.

DESIGN:

A retrospective chart review of patients admitted or referred for advanced heart failure, due to anabolic-androgenic steroid abuse, in the period 2009-2013 was performed.

RESULTS:

In 6 of 9 patients (median age: 31, all males) referred in the study period, some potential for recovery of left ventricular (LV) function was seen (P < 0.002), with a maximal improvement in LV ejection fraction reached within 6 months of treatment with angiotensin-converting enzyme inhibitors and beta-blockers. The remaining 3 patients required implantation of a LV assist device (LVAD) and were listed for heart transplantation. No recovery of LV function in the patients treated with assist device was seen.

CONCLUSION:

Anabolic-androgenic steroid-induced advanced heart failure is generally not a reversible condition. If diagnosed in the early stages some recovery of ventricular function is possible, but the long-term prognosis is uncertain. Likely, a substantial proportion of patients will eventually require LVADs or cardiac transplantation.

KEYWORDS:

AAS; anabolic; androgenic; heart failure; steroids

PMID:
25335124
DOI:
10.3109/14017431.2014.976837
[Indexed for MEDLINE]

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