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Rom J Morphol Embryol. 2014;55(3):905-8.

Inhibin alpha-subunit, Melan A and MNF116 in pheochromocytomas.

Author information

1
"Prof. Dr. Dorin Hociota" Institute of Phono-Audiology and ENT Functional Surgery, Bucharest, Romania; madalina.georgescu@gecad.com.

Abstract

AIM:

The aim of this study was to make immunohistochemical analyses with Inhibin alpha-subunit, Melan A and MNF116 (pan-Cytokeratin antibody) in pheochromocytomas, because immunohistochemistry is useful for the distinction between adrenal tumors.

PATIENTS AND METHODS:

We used 20 patients with pheochromocytomas submitted to laparoscopic (n=19) or classical (n=1) surgery and we have explored immuno-staining with Inhibin alpha-subunit, Melan A and MNF116 in these tumors. This can be helpful when we cannot make the distinction between adrenal tumors.

RESULTS:

Pheochromocytomas did not stain with Inhibin alpha-subunit, Melan A and MNF116.

CONCLUSIONS:

In our study, Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.

PMID:
25329118
[Indexed for MEDLINE]
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