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Pediatr Dermatol. 2015 Jul-Aug;32(4):522-5. doi: 10.1111/pde.12419. Epub 2014 Oct 16.

Ophthalmic Rosacea: Case Report in a Child and Treatment Recommendations.

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Department of Dermatology, Eberhard-Karls-University, Tübingen, Germany.
Medical Directorate, University Hospital of Zürich, Zürich, Switzerland.
Department of Ophthalmology, Eberhard-Karls-University, Tübingen, Germany.


We report a rare case of rosacea with ocular involvement in a child that remitted with prolonged anti-inflammatory oral tetracycline therapy and provide general expert recommendations. A 14-year-old girl presented with discrete papules and pustules on both cheeks with blepharitis and conjunctivitis. Ophthalmologic examination confirmed bilateral severe blepharitis, as well as a corneal infiltrate in the right eye with additional neovascularization. The diagnosis of rosacea with ocular involvement was made. In addition to the existing antibiotic and anti-inflammatory topical eye therapy, systemic treatment with minocycline 50 mg twice a day was started. After marked improvement, the dose was reduced to 50 mg once a day. After further amelioration, treatment was switched to maintenance therapy with 40 mg of prolonged-release doxycycline. Three years after a 12-month course of anti-inflammatory therapy, the patient remained recurrence free.

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