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Clin Infect Dis. 2015 Feb 1;60(3):453-62. doi: 10.1093/cid/ciu779. Epub 2014 Oct 13.

Diagnosing and managing diabetes in HIV-infected patients: current concepts.

Author information

1
Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
2
Division of Infectious Diseases, Weill Cornell Medical College, New York, New York.
3
Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Abstract

Diabetes mellitus (DM) is a common condition with significant associated morbidity and mortality. DM diagnosis and management among human immunodeficiency virus (HIV)-infected patients is a particularly relevant topic as the HIV-infected population ages and more HIV-infected individuals live with chronic medical comorbidities. Although there is mixed evidence regarding HIV as an independent risk factor for DM, multiple factors related to HIV and its treatment are associated with DM. This review covers the epidemiology of DM in HIV-infected patients, and diagnosis, management, and treatment goals for DM in HIV-infected patients. We highlight the most recent DM treatment guidelines from the American Diabetes Association and the European Association for the Study of Diabetes, emphasizing individualization of DM medication therapy and treatment goals. Finally, we review a comprehensive approach to cardiovascular disease risk reduction in HIV-infected patients with DM and measures to prevent other complications of DM.

KEYWORDS:

CVD; HIV; diabetes mellitus

PMID:
25313249
DOI:
10.1093/cid/ciu779
[Indexed for MEDLINE]

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