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J Gen Virol. 2015 Feb;96(Pt 2):254-8. doi: 10.1099/vir.0.070821-0. Epub 2014 Oct 13.

Canine susceptibility to human influenza viruses (A/pdm 09H1N1, A/H3N2 and B).

Author information

1
Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea University of Science and Technology, Daejeon, Republic of Korea.
2
Research Evaluation Team, Institute for Basic Science, Daejeon, Republic of Korea.
3
Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
4
Research Unit, Green Cross Veterinary Product, Yongin, Gyeonggi, Republic of Korea.
5
Korea Zoonosis Research Institute, Chonbuk National University, Jeonju, Jeonbuk, Republic of Korea.
6
Biomedical Translational Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
7
Animal and Plant Quarantine Agency, Anyang, Gyeonggi, Republic of Korea jkfrancis@korea.ac.kr andj67@korea.kr.
8
Department of Pharmacy, College of Pharmacy, Korea University, Sejong, Republic of Korea jkfrancis@korea.ac.kr andj67@korea.kr.

Abstract

We investigated the infectivity and transmissibility of the human seasonal H3N2, pandemic (pdm) H1N1 (2009) and B influenza viruses in dogs. Dogs inoculated with human seasonal H3N2 and pdm H1N1 influenza viruses exhibited nasal shedding and were seroconverted against the viruses; this did not occur in the influenza B virus-inoculated dogs. Transmission of human H3N2 virus between dogs was demonstrated by observing nasal shedding and seroconversion in naïve dogs after contact with inoculated dogs. The seroprevalence study offered evidence of human H3N2 infection occurring in dogs since 2008. Furthermore, serological evidence of pdm H1N1 influenza virus infection alone and in combination with canine H3N2 virus was found in the serum samples collected from field dogs during 2010 and 2011. Our results suggest that dogs may be hosts for human seasonal H3N2 and pdm H1N1 influenza viruses.

PMID:
25312584
DOI:
10.1099/vir.0.070821-0
[Indexed for MEDLINE]

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