Format

Send to

Choose Destination
Clin Nutr. 2015 Apr;34(2):171-80. doi: 10.1016/j.clnu.2014.08.017. Epub 2014 Sep 21.

ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults.

Author information

1
Center for Chronic Intestinal Failure, St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. Electronic address: loris.pironi@unibo.it.
2
Tumor Biology Center, Albert-Ludwigs-University, Freiburg, Germany.
3
Tayside Nutrition Managed Clinical Network, Dundee, UK.
4
Faculty of Medicine, University of Milan, Milan, Italy.
5
Nutritional Support Unit, University Hospital Vall d'Hebron, Barcelona, Spain.
6
Nutrition Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
7
University of East Anglia, Norwich Research Park, Norwich, UK.
8
The Lennard-Jones Intestinal Failure Unit, St Mark's Hospital and Academic Institute, Harrow, UK.
9
National Intestinal Failure Service, Auckland City Hospital (AuSPEN), Auckland, New Zealand.
10
Centre for Nutrition and Bowel Disease, Department of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.
11
Rigshospitalet, Department of Gastroenterology, Copenhagen, Denmark.
12
Centre for Intestinal Failure, Department of Gastroenterology and Nutritional Support, Hôpital Beaujon, Clichy, France.
13
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota and Oley Foundation for Home Parenteral and Enteral Nutrition, Albany, NY, USA.
14
General and Oncology Surgery Unit, Stanley Dudrick's Memorial Hospital, Skawina, Poland.
15
Dept. of Gastroenterologic Surgery, University Hospital North-Norway, Tromso, Norway.
16
Department of Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.
17
Department for Perioperative Nutrition, Clinic for General Surgery, Military Medica Academy, Belgrade, Serbia.
18
Medico-Surgical Department of Gastroenterology, Hôpital Erasme, Free University of Brussels, Belgium.
19
Intestinal Failure Unit, Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
20
Gastroenterology and Clinical Nutrition, CHU of Nice, University of Nice Sophia Antipolis, Nice, France.
21
Intestinal failure Unit, Salford Royal Hospital, Salford, UK.

Abstract

BACKGROUND & AIMS:

Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its "home artificial nutrition and chronic IF" and "acute IF" special interest groups to write recommendations on these issues.

METHODS:

After a Medline Search, in December 2013, for "intestinal failure" and "review"[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.

RESULTS:

The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as "the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth".

CONCLUSIONS:

This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

KEYWORDS:

Chronic intestinal pseudo-obstruction; Enterocutaneous fistulas; Home parenteral nutrition; Intestinal failure; Intestinal transplantation; Short bowel syndrome

PMID:
25311444
DOI:
10.1016/j.clnu.2014.08.017
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center