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Chem Commun (Camb). 2014 Dec 4;50(93):14613-5. doi: 10.1039/c4cc06612j.

Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative.

Author information

1
Department of Chemistry, University of Toronto, Toronto M5S 3H6, Canada. awoolley@chem.utoronto.ca.

Abstract

A tetra-ortho-chloro substituted azobenzene unit was incorporated into a photoswitchable tethered ligand for ionotropic glutamate receptors. This compound confers the modified protein with the unusual optical responses of the substituted azo scaffold permitting channel opening with yellow and red light and channel closing with blue light.

PMID:
25311049
DOI:
10.1039/c4cc06612j
[Indexed for MEDLINE]

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