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Diagn Microbiol Infect Dis. 2014 Dec;80(4):327-9. doi: 10.1016/j.diagmicrobio.2014.09.002. Epub 2014 Sep 6.

Serum inhibitory and bactericidal activity of telavancin in non-infected subjects with severe renal impairment or end-stage renal disease.

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Theravance Biopharma US, Inc., 901 Gateway Boulevard, South San Francisco, CA 94080, USA. Electronic address:
JMI Laboratories, 345 Beaver Kreek Center, Suite A, North Liberty, IA 52317, USA.


Telavancin biological activity, determined by serum titers against a reference strain of Staphylococcus aureus, was maintained in the serum of subjects with severe renal impairment or end-stage renal disease suggesting that there is no apparent effect of renal function on in vitro activity of telavancin.


Renal impairment; Staphylococcus aureus; Telavancin

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