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J Neurol Surg B Skull Base. 2014 Oct;75(5):293-300. doi: 10.1055/s-0033-1361837. Epub 2014 Jun 26.

Anatomy and cellular constituents of the human olfactory mucosa: a review.

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Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.
Department of ENT, Royal National Throat Nose and Ear Hospital, London, United Kingdom.


Studies using animal models have recently suggested that the olfactory mucosa may be a source of cells capable of stimulating and contributing to complex neurologic regeneration. Several groups have already transplanted cell derivatives from the olfactory mucosa into injury models, and the results so far have been promising. To fully appreciate the meaning of these experiments, a better understanding of the cellular biology and physiology of the olfactory system is necessary. It is therefore of utmost importance for us to first identify and understand its constituents.


olfactory ensheathing cells; olfactory mucosa; olfactory system; spinal cord repair

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