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Vet Clin North Am Equine Pract. 2014 Dec;30(3):641-58. doi: 10.1016/j.cveq.2014.08.001. Epub 2014 Oct 7.

Lawsonia intracellularis and equine proliferative enteropathy.

Author information

1
Department of Veterinary Science, Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA.
2
McGee Medicine Center, Hagyard Equine Medical Institute, 4250 Iron Works Pike, Lexington, KY 40511, USA.
3
Department of Veterinary Science, Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA. Electronic address: nslovis@hagyard.com.

Abstract

Lawsonia intracellularis is the etiologic agent for equine proliferative enteropathy (EPE), which typically affects weanling and yearling horses. In North America, EPE cases often occur between August and January, although cases outside of this time frame have been reported. Clinical signs of EPE are usually nonspecific and include lethargy, pyrexia, anorexia, peripheral edema, weight loss, colic, and diarrhea. Diagnosis is based on the presence of hypoproteinemia and hypoalbuminemia along with clinical signs and positive commercial serologic and/or molecular testing. Treatment requires the use of antimicrobials with good intracellular penetration and supportive care to prevent or decrease secondary complications.

KEYWORDS:

EPE; Equine proliferative enteropathy; Lawsonia intracellularis

PMID:
25300636
DOI:
10.1016/j.cveq.2014.08.001
[Indexed for MEDLINE]

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