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Evid Based Complement Alternat Med. 2014;2014:140724. doi: 10.1155/2014/140724. Epub 2014 Sep 11.

Mindfulness-based therapies in the treatment of functional gastrointestinal disorders: a meta-analysis.

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1
Canadian College of Naturopathic Medicine, 1255 Sheppard Ave East, Toronto, ON, Canada M2K 1E2.

Abstract

BACKGROUND:

Functional gastrointestinal disorders are highly prevalent and standard treatments are often unsatisfactory. Mindfulness-based therapy has shown benefit in conditions including chronic pain, mood, and somatization disorders.

OBJECTIVES:

To assess the quality and effectiveness reported in existing literature, we conducted a meta-analysis of mindfulness-based therapy in functional gastrointestinal disorders.

METHODS:

Pubmed, EBSCO, and Cochrane databases were searched from inception to May 2014. Study inclusion criteria included randomized, controlled studies of adults using mindfulness-based therapy in the treatment of functional gastrointestinal disorders. Study quality was evaluated using the Cochrane risk of bias. Effect sizes were calculated and pooled to achieve a summary effect for the intervention on symptom severity and quality of life.

RESULTS:

Of 119 records, eight articles, describing seven studies, met inclusion criteria. In six studies, significant improvements were achieved or maintained at the end of intervention or follow-up time points. The studies had an unclear or high risk of bias. Pooled effects were statistically significant for IBS severity (0.59, 95% CI 0.33 to 0.86) and quality of life (0.56, 95% CI 0.47 to 0.79).

CONCLUSION:

Studies suggest that mindfulness based interventions may provide benefit in functional gastrointestinal disorders; however, substantial improvements in methodological quality and reporting are needed.

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