Format

Send to

Choose Destination
BJOG. 2015 Nov;122(12):1625-9. doi: 10.1111/1471-0528.13103. Epub 2014 Oct 7.

Serum anti-Mullerian hormone levels across different ethnic groups: a cross-sectional study.

Author information

1
Homerton Fertility Centre, Homerton University Hospital, London, UK.

Abstract

OBJECTIVE:

To assess whether ethnic differences in serum anti-Mullerian hormone (AMH) exist in a population of subfertile women presenting to a fertility clinic.

DESIGN:

Observational cross-sectional study.

SETTING:

Homerton University Hospital Fertility Centre, London, UK.

POPULATION:

A total of 865 women attending the fertility clinic for their first consultation appointment between September 2012 and September 2013.

METHODS:

Serum AMH was compared amongst women from five different ethnic groups.

MAIN OUTCOME MEASURES:

Serum AMH and ethnicity were the primary outcome variables.

RESULTS:

Although initial comparison showed South Asian women to have a higher serum AMH, compared with white European and Afro-Caribbean women (F = 3.817; P < 0.005), South Asian women attending the clinic were significantly younger and less likely to be smokers than women from other ethnic groups. The prevalence of polycystic ovary syndrome (PCOS) was significantly higher in South Asian and South East Asian women than in other ethnic groups. Differences in serum AMH were no longer significant after controlling for confounding factors: age, body mass index (BMI), and smoking status with (P = 0.869) and without (P = 0.215) controlling for PCOS.

CONCLUSION:

The results from our study show that there was no independent association of ethnicity and serum AMH levels in an unselected population of women attending the fertility clinic.

KEYWORDS:

Ethnicity; infertility; serum AMH

PMID:
25286823
DOI:
10.1111/1471-0528.13103
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center