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Long-term treatment of acne with 20% azelaic acid cream.

Author information

1
First Clinic of Dermatology, University of Milan, Italy.

Abstract

Preliminary clinical studies (2) proved the effectiveness of topical azelaic acid (AZA) in the treatment of acne vulgaris. During the period of 1982-86 we carried out two studies with 20% AZA cream in patients with acne to determine its clinical indications and therapeutic schedules. The first, open study was of 100 unselected patients of either sex, while a second group of 30 patients formed a part of a larger (309 patients) multicentre single-blind comparison of topical AZA vs. 5% benzoylperoxide (BPO) gel for the treatment of papulopustular acne. The rates of improvement obtained indicate that topical AZA can be considered an effective therapy chiefly for papulo-pustular acne, with a very good local tolerance.

PMID:
2528258
[Indexed for MEDLINE]

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