In this study, we revealed that a Mekabu (Udaria pinnantifida) extract enhanced immunoglobulin (Ig) production of mouse spleen lymphocytes. Furthermore, it was suggested that water-soluble and high molecular weight ingredients in the Mekabu extract have significant enhancing effect on Ig production. Therefore, fucoidan was estimated as the active component.
Keywords: Mekabu (Undaria pinnatifida); fucoidan; immunoglobulin (Ig); mouse spleen lymphocytes; water extract.