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Bioinformatics. 2015 Feb 1;31(3):447-8. doi: 10.1093/bioinformatics/btu642. Epub 2014 Oct 1.

OrthoInspector 2.0: Software and database updates.

Author information

1
LBGI, Computer Science Department, ICube, UMR 7357, University of Strasbourg, CNRS, Fédération de médecine translationnelle, 4 rue Kirschleger 67085 Strasbourg, France and Department of Life Sciences, Natural History Museum, Cromwell Road, London SW7 5BD LBGI, Computer Science Department, ICube, UMR 7357, University of Strasbourg, CNRS, Fédération de médecine translationnelle, 4 rue Kirschleger 67085 Strasbourg, France and Department of Life Sciences, Natural History Museum, Cromwell Road, London SW7 5BD.
2
LBGI, Computer Science Department, ICube, UMR 7357, University of Strasbourg, CNRS, Fédération de médecine translationnelle, 4 rue Kirschleger 67085 Strasbourg, France and Department of Life Sciences, Natural History Museum, Cromwell Road, London SW7 5BD.

Abstract

SUMMARY:

We previously developed OrthoInspector, a package incorporating an original algorithm for the detection of orthology and inparalogy relations between different species. We have added new functionalities to the package. While its original algorithm was not modified, performing similar orthology predictions, we facilitated the prediction of very large databases (thousands of proteomes), refurbished its graphical interface, added new visualization tools for comparative genomics/protein family analysis and facilitated its deployment in a network environment. Finally, we have released three online databases of precomputed orthology relationships.

AVAILABILITY:

Package and databases are freely available at http://lbgi.fr/orthoinspector with all major browsers supported.

CONTACT:

odile.lecompte@unistra.fr

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

PMID:
25273105
DOI:
10.1093/bioinformatics/btu642
[Indexed for MEDLINE]

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