Format

Send to

Choose Destination
Nat Rev Neurosci. 2014 Nov;15(11):732-44. doi: 10.1038/nrn3827. Epub 2014 Oct 1.

Time cells in the hippocampus: a new dimension for mapping memories.

Author information

1
Center for Memory and Brain, Boston University, Boston, Massachusetts 02215, USA.

Abstract

Recent studies have revealed the existence of hippocampal neurons that fire at successive moments in temporally structured experiences. Several studies have shown that such temporal coding is not attributable to external events, specific behaviours or spatial dimensions of an experience. Instead, these cells represent the flow of time in specific memories and have therefore been dubbed 'time cells'. The firing properties of time cells parallel those of hippocampal place cells; time cells thus provide an additional dimension that is integrated with spatial mapping. The robust representation of both time and space in the hippocampus suggests a fundamental mechanism for organizing the elements of experience into coherent memories.

PMID:
25269553
PMCID:
PMC4348090
DOI:
10.1038/nrn3827
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center