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Nutrients. 2014 Sep 29;6(10):4032-42. doi: 10.3390/nu6104032.

Green tea consumption affects cognitive dysfunction in the elderly: a pilot study.

Author information

1
Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. s13403@u-shizuoka-ken.ac.jp.
2
Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. hyamada@u-shizuoka-ken.ac.jp.
3
White Cross Nursing Home, 2-26-1 Suwa-cho, Higashimurayama, Tokyo 189-0021, Japan. hide1844@wa2.so-net.ne.jp.
4
Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. parkmjjp@yahoo.co.jp.
5
Department of Drug Evaluation and Informatics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan. m08129@u-shizuoka-ken.ac.jp.
6
Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. j-nakase@itoen.co.jp.
7
Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. y-ukawa@itoen.co.jp.
8
Central Research Institute, ITO EN, Ltd., 21 Mekami, Makinohara, Shizuoka 421-0516, Japan. y-sagesaka@itoen.co.jp.

Abstract

Green tea is known to have various health benefits for humans. However, the effect of green tea consumption on cognitive dysfunction remains to be clinically verified. We conducted a clinical study to investigate the effects of green tea consumption on cognitive dysfunction. Twelve elderly nursing home residents with cognitive dysfunction (Mini-Mental State Examination Japanese version (MMSE-J) score: <28) participated in the study (2 men, 10 women; mean age, 88 years). The participants consumed green tea powder 2 g/day for 3 months. After three months of green tea consumption, the participants' MMSE-J scores were significantly improved (before, 15.3 ± 7.7; after, 17.0 ± 8.2; p = 0.03). This result suggests that green tea consumption may be effective in improving cognitive function or reducing the progression of cognitive dysfunction; however, long-term large-scale controlled studies are needed to further clarify the effect.

PMID:
25268837
PMCID:
PMC4210905
DOI:
10.3390/nu6104032
[Indexed for MEDLINE]
Free PMC Article

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