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Ann N Y Acad Sci. 2014 Sep;1325:108-26. doi: 10.1111/nyas.12529.

Strategy for prevention of cancers of the esophagus.

Author information

1
National Center for Global Health and Medicine, Tokyo, Japan.

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the animal reflux-inflammation models for Barrett's esophagus and esophageal adenocarcinoma; genomic/epigenomic analyses; eflornithine-based combinations; the molecular derangements that promote neoplastic transformation; the role of COX-2 inhibitors, proton pump inhibitors, and phase II trials in Barrett's adenocarcinoma; statins in chemoprevention and treatment of esophageal cancer; and biomarkers as potential targets in Barrett's adenocarcinoma.

KEYWORDS:

Barrett's adenocarcinoma; COXIBs, PPIs; OESO; animal reflux-inflammation models; biomarkers; elofrnithine; statins

PMID:
25266020
DOI:
10.1111/nyas.12529
[Indexed for MEDLINE]

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