Format

Send to

Choose Destination
PLoS One. 2014 Sep 29;9(9):e107232. doi: 10.1371/journal.pone.0107232. eCollection 2014.

Lactobacillus rossiae, a vitamin B12 producer, represents a metabolically versatile species within the Genus Lactobacillus.

Author information

1
Department of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
2
Department of Microbiology, University College Cork, Cork, Ireland.
3
Department of Bioscience, Biotechnology and Biopharmaceutical, University of Bari Aldo Moro, Bari, Italy.
4
Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
5
Department of Bioscience, Biotechnology and Biopharmaceutical, University of Bari Aldo Moro, Bari, Italy; Institute of Biomembranes and Bioenergetics (IBBE), CNR, Bari, Italy; National Institute of Biostructures and Biosystems (INBB), Rome, Italy.
6
Department of Microbiology, University College Cork, Cork, Ireland; Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.

Abstract

Lactobacillus rossiae is an obligately hetero-fermentative lactic acid bacterium, which can be isolated from a broad range of environments including sourdoughs, vegetables, fermented meat and flour, as well as the gastrointestinal tract of both humans and animals. In order to unravel distinctive genomic features of this particular species and investigate the phylogenetic positioning within the genus Lactobacillus, comparative genomics and phylogenomic approaches, followed by functional analyses were performed on L. rossiae DSM 15814T, showing how this type strain not only occupies an independent phylogenetic branch, but also possesses genomic features underscoring its biotechnological potential. This strain in fact represents one of a small number of bacteria known to encode a complete de novo biosynthetic pathway of vitamin B12 (in addition to other B vitamins such as folate and riboflavin). In addition, it possesses the capacity to utilize an extensive set of carbon sources, a characteristic that may contribute to environmental adaptation, perhaps enabling the strain's ability to populate different niches.

PMID:
25264826
PMCID:
PMC4180280
DOI:
10.1371/journal.pone.0107232
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Public Library of Science Icon for PubMed Central
Loading ...
Support Center