Lipids and RNA virus replication

Kouacou V Konan; Lorena Sanchez-Felipe

doi:10.1016/j.coviro.2014.09.005

Lipids and RNA virus replication

Curr Opin Virol. 2014 Dec:9:45-52. doi: 10.1016/j.coviro.2014.09.005. Epub 2014 Sep 28.

Authors

Kouacou V Konan¹, Lorena Sanchez-Felipe²

Affiliations

¹ Center for Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208-3479, United States. Electronic address: KonanK@mail.amc.edu.
² Center for Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208-3479, United States.

Abstract

Most viruses rely heavily on their host machinery to successfully replicate their genome and produce new virus particles. Recently, the interaction of positive-strand RNA viruses with the lipid biosynthetic and transport machinery has been the subject of intense investigation. In this review, we will discuss the contribution of various host lipids and related proteins in RNA virus replication and maturation.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Biological Transport
Host-Pathogen Interactions*
Lipid Metabolism*
RNA Viruses / physiology*
Virus Replication*

Abstract

Publication types

MeSH terms

Grants and funding