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EuroIntervention. 2014 Sep;10 Suppl U:U115-9. doi: 10.4244/EIJV10SUA17.

Transcatheter mitral valve implantation with Tiara bioprosthesis.

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The Centre for Heart Valve Innovation, St Paul's Hospital, Vancouver, Canada.


Mitral valve surgery is the gold standard therapy for severe mitral regurgitation, but can be associated with significant morbidity and mortality. Percutaneous mitral leaflet repair has recently been established as a viable alternative to surgery, but many patients are ineligible and repair may not be optimal. Transcatheter mitral valve implantation may be an alternate therapeutic option, particularly for high-risk patients. We outline the initial preclinical and first-in-human experience with the Tiara transapical mitral valve implantation system, highlighting the ease of implantation, proven feasibility and excellent haemodynamic performance.

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