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F1000Res. 2014 Apr 7;3:88. doi: 10.12688/f1000research.3252.1. eCollection 2014.

A 13 year-old boy with post-transplantation lymphoproliferative disorder presenting with obscure gastrointestinal bleeding: a case report.

Author information

1
Division of Gastroenterology, Department of Medicine, Case Western Reserve University/Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
2
Department of Pathology and Laboratory Medicine, University of California San Francisco, CA, San Francisco, 94131, USA.
3
Department of Pediatrics, University of California San Francisco, San francisco, CA, 94131, USA.
4
Division of Gastroenterology, Department of Medicine, University of California San Francisco, San Francisco, CA, 94131, USA.

Abstract

One well recognized and potentially serious complication of chronic immunosuppression in organ transplant recipients is post-transplantation lymphoproliferative disorders (PTLD). This accounts for 20% of all malignancies in transplant recipients, which is four times higher than the general population (1,2). The diagnosis of PTLD is often difficult, due to various manifestations resulting in late diagnosis. We report an unusual presentation of PTLD in a pediatric patient where the diagnosis was achieved only after extensive investigation.

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