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Prenat Diagn. 1989 May;9(5):365-7.

Translocation trisomy 21 in CVS not found in embryoblast: three different cell lines in CVS, amnion- and placental culture.

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1
Institute für Klinische Genetik und Zytologie, Oberhausen, F.R.G.

Abstract

Chorionic villus samples from a healthy pregnant female were obtained for first-trimester prenatal diagnosis. A translocation trisomy 21 was diagnosed. A consecutive amniocentesis revealed a normal male karyotype. At term a healthy boy was born. Cytogenetic analysis from cord blood showed a regular karyotype of 46,XY, whereas in term placenta a pathological karyotype of 47,XY, +mar was found.

PMID:
2524726
[Indexed for MEDLINE]
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