Vertebral involvement in Paget's disease: morphological classification of CT and MR appearances

Anthony Dohan; Caroline Parlier-Cuau; Rachid Kaci; Sebastien Touraine; Valérie Bousson; Jean-Denis Larédo

doi:10.1016/j.jbspin.2014.07.009

Vertebral involvement in Paget's disease: morphological classification of CT and MR appearances

Joint Bone Spine. 2015 Jan;82(1):18-24. doi: 10.1016/j.jbspin.2014.07.009. Epub 2014 Sep 22.

Authors

Anthony Dohan¹, Caroline Parlier-Cuau², Rachid Kaci³, Sebastien Touraine², Valérie Bousson², Jean-Denis Larédo²

Affiliations

¹ Department of Body and Interventional Imaging, Hôpital Lariboisière, AP-HP, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France; Université Paris-Diderot, Sorbonne Paris Cité, 10, rue de Verdun, 75010 Paris, France. Electronic address: anthony.dohan@lrb.aphp.fr.
² Université Paris-Diderot, Sorbonne Paris Cité, 10, rue de Verdun, 75010 Paris, France; Serivce de radiologie ostéo-articulaire, Hôpital Lariboisière, AP-HP, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France.
³ Service d'anatomopathologie, Hôpital Lariboisière, AP-HP, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France.

PMID: 25245640
DOI: 10.1016/j.jbspin.2014.07.009

Abstract

Vertebral Paget's disease produces a large panel of radiologic appearances sometimes atypical and pseudotumoral. Classical classifications of bone alterations based on pathophysiological hypotheses do not always match the imaging findings. This article will review the computed tomography (CT) and magnetic resonance imaging (MRI) features of Paget's disease of the spine with special emphasis on morphological findings that differentiate Paget's disease from tumors. Combined CT and MRI analyses usually provide the diagnosis of Paget's disease.

Keywords: Computed tomography; Magnetic resonance imaging; Paget's disease; Spine.

MeSH terms

Diagnosis, Differential
Humans
Magnetic Resonance Imaging
Osteitis Deformans / classification
Osteitis Deformans / diagnosis*
Osteitis Deformans / epidemiology
Osteitis Deformans / physiopathology
Spine / diagnostic imaging*
Spine / pathology*
Tomography, X-Ray Computed