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Cir Cir. 2014 May-Jun;82(3):344-51.

[Immunometabolism of exercise and sedentary lifestyle].

[Article in Spanish; Abstract available in Spanish from the publisher]


in English, Spanish

Sedentary lifestyle leads to the accumulation of visceral fat. This is accompanied by the infiltration of immune cells with pro-inflammatory characteristics in adipose tissue, causing an increased release of cytokines and generating a low-grade inflammatory state. It has been associated with the development of insulin resistance, atherosclerosis, neurodegeneration, and development of tumors. Exercise can be used as a treatment to improve symptoms of many of these conditions because it promotes an anti-inflammatory effect. In this review we analyze the pro-inflammatory factors present in obesity and the induction of antiinflammatory factors that occur with exercise.


Low-grade inflammation; anti-inflammatory cytokines; citocinas anti-inflamatorias; citocinas proinflamatorias.; ejercicio físico; exercise; inflamación de bajo grado; obesidad; obesity; pro-inflammatory cytokines

[PubMed - indexed for MEDLINE]
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