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Food Chem. 2015 Feb 15;169:372-80. doi: 10.1016/j.foodchem.2014.07.102. Epub 2014 Jul 30.

Multiresidue analysis of over 200 pesticides in cereals using a QuEChERS and gas chromatography-tandem mass spectrometry-based method.

Author information

1
Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191, PR China.
2
Agilent Technologies (China) Company, Ltd., Beijing 100102, PR China.
3
Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191, PR China. Electronic address: xwliu2006@163.com.

Abstract

A simple and high-throughput multiresidue pesticide analysis method was developed and validated for 219 pesticides in cereals (corn, wheat flour and rice) based on QuEChERS (quick, easy, cheap, effective, rugged, and safe) procedure combined with gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). Different buffer system (acetate- and citrate-buffered) and sample to solvent ratios (sample amount) were compared in the modified QuEChERS procedure to get better recovery and clean-up results. The limits of quantification (LOQ) ranged between 5 and 50μgkg(-)(1), and for the majority of the pesticides the LOQ were 5μgkg(-)(1), which were below the regulatory maximum residue limits. The coefficient of determination (r(2)) was >0.99 within the calibration linearity range of 2-200μgkg(-)(1) for the majority of the pesticides. Most recoveries at 5, 10, 20, 50, 100 and 200μgkg(-)(1) were in the range 70-120% (n=6) with associated RSDs<20% indicating satisfactory accuracy.

KEYWORDS:

Cereal; Gas chromatography–tandem mass spectrometry; Multiresidue analysis; QuEChERS

PMID:
25236240
DOI:
10.1016/j.foodchem.2014.07.102
[Indexed for MEDLINE]

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