Format

Send to

Choose Destination
Fertil Steril. 2014 Nov;102(5):1439-43. doi: 10.1016/j.fertnstert.2014.07.1255. Epub 2014 Sep 16.

Association of antimüllerian hormone levels with menstrual-cycle type and dysmenorrhea in young asymptomatic women.

Author information

1
Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Anthropology, University of Washington, Seattle, Washington. Electronic address: moe@humeco.m.u-tokyo.ac.jp.
2
Department of Environment Systems, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan.
3
Department of Environment Systems, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan; School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.
4
Faculty of Nursing, Tokyo Healthcare University, Tokyo, Japan.

Abstract

OBJECTIVE:

To examine the association between antimüllerian hormone (AMH) levels and menstrual-cycle and lifestyle characteristics among young Japanese women.

DESIGN:

Cross-sectional study.

SETTING:

University.

PATIENT(S):

Female students aged 20-22 years (n=65) who had never used oral contraceptives.

INTERVENTION(S):

Participants completed a questionnaire on reproductive and lifestyle characteristics, and kept a menstrual-cycle diary for 5 consecutive months. Serum AMH was measured once during the study period.

MAIN OUTCOME MEASURE(S):

Serum AMH concentration.

RESULT(S):

Compared with women with very mild menstrual pain, serum AMH concentration was 49.6% (95% CI 6.5%-72.8%) lower among women with severe menstrual pain. Higher AMH concentration was associated with irregular menstrual cycles. Even after adjusting for menstrual-cycle regularity and its interaction, more-severe menstrual pain was associated with significantly lower AMH concentration.

CONCLUSION(S):

Circulating AMH concentration was significantly lower among young Japanese women who had more-severe menstrual pain. Underlying physiological mechanisms need to be addressed in future studies.

KEYWORDS:

Antimüllerian hormone; menstrual pain; menstrual-cycle regularity; young women

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center