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Trends Immunol. 2014 Oct;35(10):454-6. doi: 10.1016/j.it.2014.08.009. Epub 2014 Sep 12.

Common mechanisms activate plant guard receptors and TLR4.

Author information

1
Boston Children's Hospital and Harvard Medical School, Boston, MA 02446, USA. Electronic address: jonathan.kagan@childrens.harvard.edu.

Abstract

In metazoans, the innate immune system uses Pattern Recognition Receptors to detect conserved microbial products, whereas in plants Guard Receptors detect virulence factors or activities encoded by pathogens. In a recent study, Williams and colleagues report that plant Guard receptors can be activated by a mechanism remarkably similar to that of mammalian Toll-like Receptor 4.

PMID:
25224694
PMCID:
PMC4186901
DOI:
10.1016/j.it.2014.08.009
[Indexed for MEDLINE]
Free PMC Article

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