Abstract
We developed a facile one-step approach to synthesize DNA-templated Ag/Pt bimetallic nanoclusters (DNA-Ag/Pt NCs), which possess highly-efficient peroxidase-like catalytic activity. With this finding, an aptamer based sandwich-type strategy is employed to design a label-free colorimetric aptasensor for the protein detection with high sensitivity and selectivity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aptamers, Nucleotide / chemistry
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Catalysis
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Colorimetry*
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DNA / chemistry*
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Hydrogen Peroxide / chemistry
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Metal Nanoparticles / chemistry*
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Peroxidase / metabolism
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Platinum / chemistry*
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Silver / chemistry*
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Thrombin / analysis*
Substances
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Aptamers, Nucleotide
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Silver
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Platinum
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DNA
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Hydrogen Peroxide
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Peroxidase
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Thrombin