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Genome Biol. 2014 Aug 30;15(8):452. doi: 10.1186/s13059-014-0452-9.

Cancer genomics: one cell at a time.

Abstract

The study of single cancer cells has transformed from qualitative microscopic images to quantitative genomic datasets. This paradigm shift has been fueled by the development of single-cell sequencing technologies, which provide a powerful new approach to study complex biological processes in human cancers.

PMID:
25222669
PMCID:
PMC4281948
DOI:
10.1186/s13059-014-0452-9
[Indexed for MEDLINE]
Free PMC Article

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