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Public Health Nutr. 2015 Jun;18(8):1506-13. doi: 10.1017/S1368980014001992. Epub 2014 Sep 15.

Intensive low-glycaemic-load dietary intervention for the management of glycaemia and serum lipids among women with gestational diabetes: a randomized control trial.

Author information

1
1Guangdong General Hospital,Guangdong Academy of Medical Science,Guangzhou,People's Republic of China.
2
2Faculty of Nutrition,School of Public Health,Sun Yat-sen University,74th Zhongshan II Road,Guangzhou 510080,People's Republic of China.

Abstract

OBJECTIVE:

The present study aimed to compare the effects of a general dietary intervention and an intervention with low glycaemic load (GL) on glycaemic control, blood lipid metabolism and pregnancy outcomes in women with gestational diabetes mellitus.

DESIGN:

Participants were randomly assigned to two groups, receiving either an individualized general dietary intervention (Control group) or an intensive low-GL intervention (Low-GL group) every two weeks, from 24-26 weeks of gestation to delivery.

SETTING:

The Center of Maternal Primary Care in Guangdong General Hospital, China.

SUBJECTS:

Ninety-five women with gestational diabetes mellitus were enrolled from June 2008 to July 2009.

RESULTS:

After the intervention, both groups significantly decreased their dietary intakes of energy, fat and carbohydrate. The Low-GL group had significantly lower values for GL (122 v. 136) and glycaemic index (50 v. 54) but greater dietary fibre intake (33 v. 29 g/d) than did the Control group (all P<0·01). Significantly greater decreases in fasting plasma glucose (-0·33 v. -0·02 mmol/l, P<0·01) and 2 h postprandial glucose (-2·98 v. -2·51 mmol/l, P<0·01), significantly lower increases in total cholesterol (0·12 v. 0·23 mmol/l) and TAG (0·41 v. 0·56 mmol/l) and a significantly lower decrease in HDL cholesterol (-0·01 v. -0·11 mmol/l) were also observed in the Low-GL group compared with the Control group (all P<0·05). There were no significant differences in body weight gain, birth weight or other maternal-fetal perinatal outcomes between the two groups.

CONCLUSIONS:

The low-GL targeted dietary intervention outperformed the general dietary intervention in glycaemic control and the improvement of blood lipid levels in women with gestational diabetes mellitus.

KEYWORDS:

Gestational diabetes mellitus

PMID:
25222105
DOI:
10.1017/S1368980014001992
[Indexed for MEDLINE]

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