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Int J Environ Res Public Health. 2014 Sep 10;11(9):9345-60. doi: 10.3390/ijerph110909345.

Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial.

Author information

1
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. tiia.ngandu@thl.fi.
2
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. jaana.lindstrom@thl.fi.
3
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. esko.levalahti@thl.fi.
4
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. tiina.laatikainen@thl.fi.
5
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. markku.peltonen@thl.fi.
6
Alzheimer's Disease Research Center, Karolinska Institutet, Novum 5th floor, SE-14157 Stockholm, Sweden. Francesca.Mangialasche@ki.se.
7
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. satu.ahtiluoto@fimnet.fi.
8
Institute of Health Sciences/Geriatrics, University of Oulu and Medical Research Center Oulu, Oulu University Hospital and University of Oulu P.O. Box 5000, FI-90014, Finland. riitta.antikainen@oulu.fi.
9
Department of Neurology, Kuopio University Hospital, P.O. Box 100, FI-70029 KYS, Kuopio, Finland. tuomo.hanninen@kuh.fi.
10
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. antti.jula@thl.fi.
11
Aging Research Center, Karolinska Institutet-Stockholm University, Gävlegatan 16, SE-11330 Stockholm, Sweden. Francesca.Mangialasche@ki.se.
12
Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FI-00250 Helsinki, Finland. teemu.paajanen@ttl.fi.
13
Department of Lifestyle and Participation, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. satu.pajala@thl.fi.
14
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland.
15
Institute of Health Sciences/Geriatrics, University of Oulu and Medical Research Center Oulu, Oulu University Hospital and University of Oulu P.O. Box 5000, FI-90014, Finland. timo.strandberg@oulu.fi.
16
Department of Chronic Disease Prevention, National Institute for Health and Welfare, P.O. Box 30, FI-00271 Helsinki, Finland. Francesca.Mangialasche@ki.se.
17
Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. tuomo.hanninen@kuh.fi.

Abstract

Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60-77 years, the dementia risk score ≥ 6) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure 140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol/L for, and fasting glucose 6.1 (0.9) mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons.

PMID:
25211775
PMCID:
PMC4199023
DOI:
10.3390/ijerph110909345
[Indexed for MEDLINE]
Free PMC Article

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