Send to

Choose Destination
See comment in PubMed Commons below
J Neuropsychiatry Clin Neurosci. 1989 Spring;1(2):188-90.

Radiologic correlates of antidepressant-induced delirium: the possible significance of basal-ganglia lesions.

Author information

  • 1Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.


Antidepressant-induced delirium in five of 60 (8%) patients over the age of 45 is reported. In each case, delirium developed within two weeks of beginning the antidepressant and appeared to be completely reversible once the medication was discontinued. Brain magnetic resonance imaging revealed basal-ganglia lesions in each patient who developed delirium. This finding indicates that patients with basal-ganglia lesions may be more vulnerable to antidepressant-induced delirium and is consistent with recent data from the neurologic and psychiatric literature that implicate the basal ganglia in the development of other types of delirium.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center