Format

Send to

Choose Destination
Lab Chip. 2014 Nov 7;14(21):4244-9. doi: 10.1039/c4lc00817k.

Open-access optical microcavities for lab-on-a-chip refractive index sensing.

Author information

1
Department of Materials, University of Oxford, OX1 3PH, UK. aurelien.trichet@materials.ox.ac.uk.

Abstract

Open-access optical microcavities provide a novel approach to label-free lab-on-a-chip optofluidic sensing. They offer direct access to a highly confined electromagnetic field, and yield a femtoliter detection volume. This article describes the characteristics of these devices for refractive index sensing. We show that most of the ambient noise can be removed from the refractive index data by simultaneous tracking of resonances across an array of cavities. A sensitivity of 3.5 × 10(-4) RIU is demonstrated which corresponds to detecting the refractive index change caused by the presence of 500,000 glucose molecules in aqueous solution.

PMID:
25208130
DOI:
10.1039/c4lc00817k

Supplemental Content

Full text links

Icon for Royal Society of Chemistry
Loading ...
Support Center